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T-bet + B cells: a common denominator in protective and autoreactive antibody responses

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For long-term use, most trials last 8-12 weeks, but a few have extended out to 12 months.44 For example, a yearlong trial in type 2 diabetes patients using 2g/day of seed powder reported sustained improvements in glucose control and cholesterol without safety concerns.45 While this is encouraging, the number of long-term studies is still small, and more work is needed to confirm safety beyond a year especially at higher TQ concentrations
