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After Phase II, a final Phase III process can modify these xenobiotic conjugates in ways that enhance the linker molecules attraction for transport proteins which pump the metabolite out of the cell.4 While this may all seem complex, the net effect of the entire process is to transform a drug molecule into a less active yet more bulky and water-soluble metabolite which can be easily excreted

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Understanding their capabilities and limitations leads to satisfaction rather than disappointment

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