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Rs1858830 MET promoter variant is also predictive of atypical functional magnetic resonance imaging (fMRI) activation and deactivation pattern of human brain to social stimuli, and it impacts functional and structural connectivity in the temporo-parietal lobes, which selectively express MET (Rudie et al., 2012

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The guidance for neurological symptoms, recommending every-other-day injections, further highlights that the standard maintenance dose is not universally sufficient
