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Current acne treatments focus on the use of doxycycline, benzoyl peroxide, isotretinoin, etc
Astrocytes are more active than neurons in synthesizing cholesterol and this renders the neurons dependent on cholesterol delivery from nearby cells for neurite extension, axonal regeneration, and synaptogenesis
This parallels the emerging therapeutic potential in animals, where GPX4-regulated ferroptosis is being explored as a strategy for treating diseases such as cancer (Yang et al., 2014
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