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For long-term maintenance, most healthcare providers recommend one B12 injection every 4 to 12 weeks

Clinical trials involving approximately 900 participants found that the adverse event profile was indistinguishable from placebo for most parameters

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Towards Cellular Targets for Therapy in SCA3: Lessons from Preclinical Models So far, we have proposed that the primary pathogenic mechanism in SCA3 is indeed the loss of normal quality control of protein folding and interactions, therefore compromising their function
