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Still, a few risks deserve attention: Absolute contraindications: Wilson's disease or any other copper metabolism disorder, active cancer (because of GHK-Cu's pro-angiogenic activity), pregnancy, and breastfeeding
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The Cardioprotective Mechanisms of Natural Products Regulating Nrf2-Associated Cellular Processes in Cardiovascular Diseases Apart from targeting the Nrf2/Keap1 interaction, some cardioprotective natural products were found to regulate Nrf2-associated cellular processes

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