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[115] This functionality is lost in vitamin B 12 deficiency, resulting in an increased homocysteine level and the trapping of folate as 5-methyl-tetrahydrofolate, from which THF (the active form of folate) cannot be recovered
10.1083/jcb.147.1.185 94

In this context, there is growing attention to research involving functional foods, and the development of this type of product has strongly influenced the market (Alongi & Anese, 2021)

Author Correction: Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial
