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Instead of being flushed away, it starts to attack liver cells, leading to oxidative damage and cellular stress
J.et al (1971)
Results may last 2-4 months, though this can vary based on individual metabolism, muscle strength, and lifestyle factors
This is also the structure Novo Nordisk's own investigational semaglutide+cagrilintide combination used in REDEFINE 1 (Garvey et al., NEJM 2025) both components stepped in parallel through a 16-week ramp rather than introduced together at maintenance
