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This conclusion is robust to adjustments for the active content and the actual dose administered

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Drawing inspiration from the reported binding modes of the known DDX3X inhibitor RK-33 [11, 23], which demonstrated that the methoxybenzyl group on the imidazolone moiety positioned toward the solvent-exposed region could serve as a starting point for molecular design

PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease