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The ultimate adverse effect of statins on glucose metabolism may be due to a stronger inhibitory effect on the pro-glucose metabolizing bacteria in the gut or a stronger promotional effect on the anti-glucose metabolizing bacteria

doi: 10.1152/ajpendo.00515.2019

For instance, memantine, an uncompetitive NMDAR antagonist, provided limited structural and electrophysiological protection in nonhuman primate OHT models [85, 86], and oral memantine did not slow glaucoma progression in clinical trials (NCT00141882, NCT00168350) [87]
