intracellular antioxidant glutathione (GSH), a powerful antioxidant, plays a Jarrow Formulas® Glutathione Reduced Intracellular

Averill-Bates, 2024

Beyond classical antioxidant signaling, GSH interfaces with additional pathways, including Hippo-Yes1 associated transcriptional regulator (YAP1) signaling to regulate GPX4 and SLC7A11 expression, 159,160 mechanistic target of rapamycin kinase (mTOR) signaling to influence GPX4 protein synthesis through cysteine metabolism, 161 and NF-B signaling to restrain inflammation-associated ROS production 162

We also verified whether LC3 is required for the hair regeneration process using a small molecule 3MA that inhibits LC3, to treat mice after dorsal hair plucking

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