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It accumulates and damages macromolecules through secondarily derived ROS (hypochlorous acid, hydroxyl radical and chloramines)

Some proteins increased in both fractions, - -Enolase is a glycolytic protein that also rapidly increases and dimerizes at the surface of activated monocytes to form a plasminogen receptor critical for immune cell recruitment to the lung [26]

While GABA alone showed improvements in some oxidative stress markers and partial restoration of excitatory-inhibitory balance, the combination therapy was more effective in reversing neurochemical and behavioral deficits associated with PPA-induced neurotoxicity

none of which can be singled out without empirical testing