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U1866A - an inhibitor of oxidosqualene cyclase, desmosterol reductase, and Niemann-Pick type C1 (NPC1) cholesterol transporter - suppresses intracellular cholesterol biosynthesis and trafficking of cholesterol from lysosomes
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112,117 Another study revealed that isoalloLCA increases nuclear receptor 4 group A1 (NR4A1) binding at the Foxp3 locus, increasing Foxp3 transcription and promoting Treg differentiation
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