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MOTS-c acts as a metabolic coordinator, linking mitochondrial health to nuclear gene expression, a critical communication system that often fails during aging and metabolic disease

The main function of SODs was to decompose superoxide radicals into molecular oxygen and hydrogen peroxide inside cells, which reaction is as follows: Based on the functional metal cofactors located at the active sites, four distinct classes of SODs have been found (Figure 1)

The blood samples assessment was carried precisely as described before [1] (Table 1)

If a patient cant tolerate allopurinol and meets the criteria (see above) for probenecid, that can be tried