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Taken together, this is the first study to describe the hepatic metabolome after ischemic AKI in a murine model and demonstrates that there is significant liver-kidney crosstalk after AKI.

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As a non-peptide growth hormone secretagogue, MK-677 serves as a valuable research tool for investigating endocrine signaling, growth hormone physiology, muscle and bone metabolism, and age-related hormonal changes in controlled laboratory environments

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