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Oxidative stress can result in vascular endothelial cell injury (83, 230234), neuronal cell compromise (66, 122, 123, 152, 156, 162, 233, 235245), alterations in neurotransmitters (69, 246, 247), myelin degradation (79, 224, 248252), cell senescence (55, 112, 253255), loss of stem cell proliferation (66, 168, 228, 241, 251, 256259), and cognitive impairment (120, 121, 200, 223, 243, 245, 260266)
Adiponectin enhances quiescence exit of murine hematopoietic stem cells and hematopoietic recovery through mTORC1 potentiation