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A major challenge that remains is to identify endogenous GPCRs that are highly expressed in a specific cell type of interest and that display the desired G protein coupling properties, as suggested by the analysis of DREADD mutant mice

Funding KS thankfully acknowledges DST-SERB CRG for providing financial support in the form of research projects (No: EMR/2017/002841 and No: CVD/2020/000604) and the Central University of Punjab for the Research Seed Money (CUPB/Acad./2022/1194, Dated 19.05.2022) to conduct the study

This work focuses on new approaches to assessing cancer progression by GR, which may then open new, exciting drug discovery opportunities and target identification opportunities

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Chen C, Wang D, Yu Y, Zhao T, Min N, Wu Y, Kang L, Zhao Y, Du L, Zhang M, et al