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Journal of Vascular Surgery , 65 (5), 1518

Given that p-cresyl sulfate, very similar to indoxyl sulfate, is notoriously difficult to eliminate by dialysis (Gryp et al., 2005), it is most likely that intervening the biosynthesis pathway is the best way to attenuate such toxic effect

Surprisingly, very similar prediction results with AUROC = 0.80 was established in this external validation cohort, suggesting that these microbiome features can be used to distinguish and predict human TMAO producer phenotypes from carnitine metabolism and have adequate potential to be applied in different populations

Problems and Prospects: Public Health Regulation of Dietary Supplements