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Experiments often involve rodent or cell-based systems and measure metabolic flux, markers in adipose and muscle tissues, and transcription patterns affected by NNMT activity

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Key Takeaway: Most "side effects" of collagen are related to digestion or the quality of the specific product

Therefore, dietary supplementation with specific probiotic species to modulate the gut microbiota could emerge as a moderate, cost-effective, and efficient auxiliary strategy for mitigating heavy metal pollutants in the human body, offering a promising direction for future public health interventions