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Description
Physiol Mol Plant Pathol

Given the widespread, universal prevalence of low vitamin D status [16], public health authorities are reassessing optimal targets, extending their focus beyond bone health to encompass broader physiological and immunological functions [17]

This is primarily mediated by aquaporin water channels (for example, AQP4) and inwardly rectifying K + channels such as Kir4.1, which are often colocalized at astrocytic endfeet adjacent to blood vessels

Iron metabolism imbalance, lipid peroxidation and the System Xc-/GSH/GPx4 axis imbalance are the three hallmarks (28)
