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Insights into scfv:drug binding using the molecular dynamics simulation and free energy calculation

Further analysis indicated that hydrogen-rich water significantly decreased the levels of ROS in the colon tissues of constipated rats, reduced malondialdehyde (MDA) content, and enhanced superoxide dismutase (SOD) activity, thereby alleviating intestinal oxidative stress

doi: 10.1038/nri978 222 MantovaniASicaASozzaniSAllavenaPVecchiALocatiM

The peptide consists of 30 amino acids (the first 29 of GHRH plus a modification) with specific chemical alterations that resist enzymatic degradation and prolong receptor activation