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however, trial participants may be randomised in a 2:1 or 3:1 ratio for reasons including cost, ethics, increased statistical power, and the potential to gain extra information on the treatment [15, 19]

Probiotic supplements have been shown to be beneficial for gastrointestinal diseases (47,48,49,50,51)

[DOI] [PubMed] [Google Scholar] 26.Grinberg L., Fibach E., Amer J., Atlas D
