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Bauer AK, Faiola B, Abernethy DJ, Marchan R, Pluta LJ, et al

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When assessing drug efficacy for the treatment of glioblastoma multiforme (GBM), currently, the most reliable models are generated through direct injection of patient-derived cells or more frequently the isolation of glioblastoma cells endowed with stem-like features and orthotopically injecting these cells into the cerebrum of immunodeficient mice

The findings revealed that 47 NtGST s displayed a collinearity relationship across the six species, indicating that during the process of evolution, tobacco GST s were highly conserved on the corresponding chromosomes