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melanotic lesion in eye Primary Acquired Melanosis (PAM) Eyelid Melanocytic Tumors | Ento
Description
Cardiovascular effects stem primarily from MC3R and MC4R activation in vascular endothelium and cardiac tissue

Loss of ER redox homeostasis can lead to ER stress and induction of the unfolded protein response (UPR) which, if severe enough will trigger cell death via the apoptotic pathway

DOI: 10.1210/en.2012-1435 [28] Roa, J

Chemical modifications of nucleic acid aptamers for therapeutic purposes
