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A clinical trial conducted in Turkey showed that nicotine dependence and anxiety levels in smokers were correlated with MetS parameters [84], and it is therefore reasonable to hypothesize that smoking cessation may alleviate MetS to some extent

Ethics statement The studies involving human participants were reviewed and approved by This research was approved by the Institutional Review Board (IRB

In some instances, adjuvant therapy (such as chemotherapy or chemoradiation) may be considered after surgery, particularly if there are certain risk factors or if lymph nodes are involved, to reduce the risk of recurrence

Cancer 122, 664671