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Additionally, the extra male hormones, coupled with lower levels of estrogen and progesterone, are also what disrupts the normal menstruation cycle and cause other physical male-traits as well as hormonal imbalance

Proteins were separated by sodium dodecyl sulfate polyacrylamide gel electrophoresis and transferred to polyvinylidene difluoride membranes (Millipore, Bedford, MA, USA)

673 Prolonged PERK activation suppresses global protein synthesis, leading to synaptic failure and neuronal death 674 These disruptions are central to the pathology of neurodegeneration, as demonstrated in animal models