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In depression, while direct evidence linking NF-B and GPX4 remains limited, it has been established that both NF-B activation and GPX4 suppression contribute to brain injury, including neuronal loss, microglial overactivation, and reduced adult hippocampal neurogenesis (AHN) (Li et al., 2021

.,BainJM,LouwJL,OkaiLE,WallsCA,BallouBE,WalkerR,ReidLA,MunroD,BrownCA,BrownAJP,GowGDErwig LPNARCandida albicans hypha formation and mannan masking of -glucan inhibit macrophage phagosome maturation.2014;5(6):e01874 40

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