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Area under the curve (AUC) was calculated for each variable measured post meal, both pre and post intervention

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Cryo-electron microscopy was used to study human mechanistic target of rapamycin complex 1 (mTORC1) activation on lysosomal membranes, showing progressive recruitment by RAGRagulator, RHEB and RAPTOR, culminating in mTORmembrane engagement and full enzyme activation.