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FoxO transcription factors regulate numerous genes coding for intra- and extracellular antioxidant proteins such as Mn-SOD and Cu,Zn-SOD, peroxiredoxin-3 and peroxiredoxin-5, mitochondrial thioredoxin (Trx2) and mitochondrial thioredoxin reductase, glutathione peroxidase 1, and selenoprotein P [143]
these can include pain, redness, or swelling at the site of the shot, which typically resolve on their own
Cancer 124(13):2740-2747, 2018
