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Chin J Obstet Gynecol Pediatr (Electron Ed)

483 Exploiting IDH1/2 mutations with 2-HG inhibitors reverses metabolic and epigenetic dysregulation, 484 whereas combination therapies incorporating metabolic inhibitors with standard treatments block metabolic plasticity and enhance therapeutic responses

Mndez-Snchez et al

Analysis of the diurnal transcriptome and proteome revealed that both mRNA and protein expression of SLC22A5 were dramatically reduced in the kidneys of cKOt mice throughout the entire circadian cycle, whereas expression of SLC22A2 was slightly increased (Figure 6E)
