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For example, C9orf72 is part of a protein complex that controls autophagosome formation and lysosomal fusion, and when impaired, leads to accumulation of TDP-43 aggregates [222]
Regulatory T cells, a viable target against airway allergic inflammatory responses in asthma
The importance of cancer cell metabolism and the limitations of conventional cancer therapies (e.g., resistance to chemotherapy or radiotherapy) have prompted the development of strategies aimed at targeting this biological process 2
