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16 Airway defenses against oxidants include airway surface mucins that can scavenge HOCl and other oxidants, 17 however, oxidant stress markedly increases mucin gene transcription, goblet cell hyperplasia and mucin granule exocytosis
Attenuation of oxidative stress and hypertension in an animal model of HELLP syndrome
Notably, high concentrations of cysteamine can inhibit -glutamylcysteine synthetase (-GCS), leading to depleted intracellular GSH stores and exacerbating oxidative stress-related conditions 12,13
Furthermore, GSH can modulate protein function via S-glutathionylation under oxidative stress
