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153 Diagnostic approaches focus on identifying impaired counterregulatory responses and may include continuous glucose monitoring systems to detect unrecognized hypoglycemic events

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Especially under ischemiareperfusion conditions, reducing the level of acylcarnitine has a significant effect on the energy metabolism of the heart and the maturity and proliferation of cardiomyocytes because reducing the utilization of fatty acids and increasing the reliance on glucose oxidation as an energy source can promote the recovery of myocardial function at a lower rate of oxygen consumption

Ojo et al., 2021), it is possible that, aging E4 carriers may display alterations in L-carnitine, L-carnitine gut metabolites, and acylcarnitine profiles in the brain and the periphery reflecting such alterations