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Description
10.1186/s12935-015-0168-2 48 ChistiakovD

Among these, the glutathione peroxidase 4 (GPX4) pathway serves as the central defense mechanism

The proteins were embedded in a box of OPC water molecules (minimum distance of 12 from the solute to the boundaries of the box) and the net charge of the system was set to zero by neutralization with Cl-ions using the program tLEaP included in AmberTools21 ( 60

Cell Line: 22Rv1 cells Concentration: 0.1 M, 0.5 M, 1 M, 10 M Incubation Time: 6 hours Result: Significant reduction of downstream phosphorylation of RNA Pol II at Ser2 and Ser7, and diminished phosphorylation at Ser5
