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10.1111/1346-8138.15743 14 BlatnikM.ThorpeS

Additional preclinical work published in Cell Chemical Biology evaluated NNMT inhibition in similar diet-induced obesity models and confirmed the pattern: significant reductions in body weight gain, adipose tissue expansion, and circulating triglycerides compared to untreated controls

Acta 1771 663676 10.1016/j.bbalip.2007.02.012 [DOI] [PubMed] [Google Scholar] Miller W

For instance, phenylacetylglutamine, a metabolite derived from microbial metabolism of dietary phenylalanine, has been associated with short sleep duration, mitochondrial dysfunction, and age-related comorbidities in humans (Fritz et al., 2023