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Crit Rev Food Sci Nutr 32:67103 [DOI] [PubMed] [Google Scholar] Shaikhali J, Heiber I, Seidel T, Strher E, Hiltscher H, Birkmann S, Dietz KJ, Baier M (2008) The redox-sensitive transcription factor Rap2.4a controls nuclear expression of 2-Cys peroxiredoxin A and other chloroplast antioxidant enzymes

Following cisplatin-induced ROS overproduction, DNA damage, and reduced ATPase activity in the inner ear, the expression of the proapoptotic protein Bax increases, while the expression of the antiapoptotic protein Bcl-2 decreases, leading to an increased Bax/Bcl-2 ratio

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We would like to point out that the only systematic review article we did not include in our review was the one related to the article by Lee et al