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It crosses the placental barrier and may have an effect on FGR and brain development

A review of sarcopenia pathophysiology, diagnosis, treatment and future direction

Kuo YC, Tsao CW

IR induced by HA worsens postmenopausal PCOS in rat models, resulting in significant abnormalities in glucose and lipid metabolism as well as cardiovascular and renal damage, including hypertension, decreased glomerular filtration rate, proteinuria, and tubular injury (Torres Fernandez et al., 2019)
