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Available online: 100.Wiest D.B., Chang E., Fanning D., Garner S., Cox T., Jenkins D.D

This suggests an increased vulnerability to oxidative damage

Due to the significant effects of thiamine on these pathways, B1 deficiencies have so significant side effects
An IV bolus can create a temporary rise in blood levels, but how useful that rise is depends on the nutrient, dose, baseline status, and clinical goal
