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9 The TMAO taken with food is absorbed through the intestinal barrier and is detectable in blood after 15 min

Of note, there were only 45 patients in this trial and there was no placebo arm

Aging Clin Exp Res 33:28872898 Prasada Kabekkodu S, Chakrabarty S, Jayaram P, Mallya S, Thangaraj K, Singh KK, Satyamoorthy K (2023) Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: implications for post-covid complications

However, there was considerable interpatient variability in plasma curcumin levels among study participants, suggesting that variable curcumin absorption and tissue distribution may be a challenge in this context