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Reactive oxygen species and endothelial functionrole of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases
Importantly, although several chemically-distinct agents, including glutamate, erastin, sulfasalazine and BSO, can all induce ferroptosis through GSH depletion, the present study extends our previous work by demonstrating that these diverse upstream perturbations converge on a shared downstream signaling axis centered on PDI
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