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In mitochondria, Grx2 has been shown to efficiently catalyze (de)glutathionylation of complex I and SOD1 [173,174]

doi: 10.1042/cs0850213

Other evidence obtained during rewarming of cold-stored rat hepatocytes, demonstrated that changes in GSH levels play a role in the mechanisms regulating apoptosis and necrosis [46]

Treating this condition is important so that individuals can regain control over their lives and comfortably perform their daily activities
