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Description
Acetylcholine (ACh) is generally the primary transmitter of interneurons, but each subtype may use various co-transmitters or neuromodulators such as 5-hydroxytryptamine (5-HT), adenosine triphosphate (ATP), tachykinin (TK), nitric oxide (NO), and somatostatin (SOM) [45]

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At week 12, 55.4% of individuals in the nicotine patch group had achieved 4 week abstinence and 40.9% of those in the placebo patch group had achieved 4 week abstinence (p=0.007)

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