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Plant Biotechnol J 4(3):200215 Yates H (2018) Cold stress and membrane fluidity
These reporters do not detect the hormone itself, but the hormone response, so they indicate where the hormone response is strongest compared to other tissues

doi: 10.1194/jlr.R300019-JLR200

Using high concentrations of hydroquinone for extended periods of time can cause an irritant contact skin reaction, and it can also lead to paradoxical darkening of the skin