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The coefficients for the 2 treatment-by-time interaction terms represent the estimated difference in the 31 P-MRS measure between groups at week 1 and at week 12, adjusted for baseline values

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FMN and FAD play an important role in bioenergetics, photochemistry, bioluminescence, redox homeostasis, chromatin remodeling, DNA repair, protein folding, and other processes [440] highly relevant for preventing a wide range of stress-related medical conditions including chronic inflammation, headaches, anemia, cancer, hyperglycaemia, hypertension, and diabetes, as summarized in Fig