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If left untreated, the bilirubin can then spread into the brain, where it causes long-term damage, which includes cerebral palsy, mental retardation, sensory difficulties, delayed speech, poor muscle coordination, learning difficulties, and enamel hypoplasia or yellowish-green staining of teeth, and even death

Up to our knowledge, our study is the first report that shows UA can protect myelin in CNS against toxin induced demyelination

2.3.5 Amplification of oxidative and nitrosative stress In SRMI, oxidative and nitrosative stress arise from a concerted overproduction of ROS/RNS across multiple cardiac cell types

Therapeutic role of melatonin on acrylamide-induced neurotoxicity via reducing ER stress, inflammation, and apoptosis in a rat model