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Notably, 4-HNE can activate the PPAR pathway, suppressing PGC-1-mediated mitochondrial biogenesis and reducing local ATP supply at synapses, thereby impairing plasticity mechanisms such as LTP (194)

Dietary and host proteins are, upon degradation, important sources of cysteine ( Figure 1 )

[DOI] [PubMed] [Google Scholar] 588.Fauland A., Trotzmuller M., Eberl A., Afiuni-Zadeh S., Kofeler H., Guo X., Lankmayr E
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