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Description
Operating parallel to glycolysis, the PPP begins with glucose-6-phosphate, a common intermediate shared by both pathways

USA 102 , 1479514800 (2005)

For adults over 65, no dose adjustment is required, but careful monitoring for adverse effects is prudent as older adults often have multiple comorbidities and medications that increase complication risk

The combination might therefore synergistically relieve Epstein-Barr virus-mediated repression by promoting both transcriptional activation (via vitamin D receptor-tumour protein p53 interaction) and post-translational stabilisation of tumour protein p53 (via curcumin-induced stress response), ultimately restoring downstream p21 expression and cell-cycle arrest
