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[DOI] [PubMed] [Google Scholar] 252.Bakula D, Scheibye-Knudsen M

186 In renal epithelial cells, claudin-16 (CLDN16) and CLDN19 are involved in divalent metal import, including magnesium

Research shows it was used at 65 mg/kg/day for six months

IDH1 mutations cause significant changes in enzymatic reactions, catalyzing the large-scale conversion of -ketoglutarate (2-KG) to 2-hydroxyglutarate (2-HG), and cause significant changes in the cells metabolic system