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Collectively, these insights firmly establish oxidative stress as a central and undeniable driver of oocyte aging, underscoring the urgent need for integrated biomedical and environmental strategies to safeguard female fertility
Sahoo PM

With age, NAD + levels decrease while NADH levels increase, leading to metabolic disorders, mitochondrial dysfunction, oxidative stress, and accelerated aging (137)

Shahdost-Fard, K
