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It has been found that estradiol benzoate, for example, causes a change in the expression of ECS components (CB 1 R, CB 2 R, FAAH) in the rat uterus, in an estrogen receptor-dependent way, indicating potential for hormonal regulation of the ECS in reproductive tissues (Maia et al., 2017)
Handb Exp Pharmacol 2014;220:67-100
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Similar to exosomes and polymeric NPs, hybrids require complex synthesis protocols and face challenges in achieving batchtobatch consistency, complicating quality control and clinical translation
